TESTING: Lyophilized Exosomes in Blinded Study
This blinded comparison study concluded that the lyophilization process, followed by reconstitution, significantly impacts the integrity of the exosome membrane, ultimately resulting in a sample that consists primarily of proteins. In contrast, saline preservation maintains the exosome membranes in a healthy state with their typical morphology, optimizing their functionality as cell-to-cell communicators, enabling them to be recognized by acceptor cells and reprogrammed accordingly
Setting the Global Standard for Exosome Safety & Efficacy
Evidence-based oversight ensuring the highest quality exosome products in aesthetic medicine
ABOUT US
Our Mission
EXACT™ unites pan-industry experts to ensure exosome safety and efficacy through independent, evidence-based oversight and collaboration.
The Exosomes Auditing Compliance and Testing Bureau (EXACT™) is committed to ensuring the safety and efficacy of exosome-based aesthetic treatments through the oversight, development, and consistent application of evidence-based standards. We collaborate with healthcare providers, manufacturers, researchers, and regulatory bodies worldwide to ensure integrity, transparency, and scientific rigor in exosome characterization, storage, and application, protecting consumers while advancing legitimate innovation in regenerative aesthetics.
EXACT™️
Core Pillars
EXACT™ is built on five foundational pillars that define our comprehensive approach to exosome industry oversight:
-
Testing. Independent lab analysis of exosome products with detailed quality reports and MISEV compliance verification.
-
Education. Evidence-based resources, webinars, and training on exosome best practices and regulatory compliance.
-
Auditing. Facility and process audits to verify and certify compliance with EXACT manufacturing standards.
-
Standards. Developing manufacturing and validation requirements aligned with FDA, ISO, and ISEV frameworks.
-
Community. Connecting stakeholders through networks and forums to advance exosome quality standards.
-
Compliance. Expert guidance on regulatory requirements, quality systems, and global standards alignment.
Explore information about Exosomes
3
THE CHALLENGE
The situation is compelling
"While exosome-based aesthetic products may have substantial potential, the industry is hindered by inconsistencies in transparency, exaggerated claims, and weak regulatory frameworks.
Future efforts should focus on standardising exosome formulations, enhancing regulatory oversight, and fostering ethical promotion to ensure consumer safety and scientific credibility. Addressing these gaps is essential for exosome-based therapies to achieve their transformative promise."
2025, The International Society of Aesthetic Plastic Surgery
"The field grapples with the complexities of harmonising exosome characterisation protocols and safeguarding therapeutic integrity."
— Rahman et al., Aesthetic Plastic Surgery, 2024
"Without the accurate and detailed profiling of exosome sources and rigorous characterisation of the exosomes, it seriously casts doubt on the scientific reliability."
— Rahman et al., Aesthetic Plastic Surgery, 2024
Exosome Insights for Informed Decision-Making
Stay ahead of the curve with our latest blog posts
